Hsp90ab1 CLIA Kit for Mouse(Mus musculus) | EIAab.comHsp90ab1 CLIA Kit for Mouse(Mus musculus)

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Hsp90ab1 (Gene name),

Heat shock protein HSP 90-beta (Protein name ), HS90B_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Hsp90ab1(Hsp84;Hsp84-1;Hspcb);

Protein name:

Heat shock protein HSP 90-beta;

Alternative:

Tumor-specific transplantation 84 kDa antigen(TSTA);Heat shock 84 kDa(HSP 84;HSP84);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer. Interacts with p53/TP53. Forms a complex with CDK6 and Hsp90/HSP90AB1 (By similarity). Interacts with UNC45A. Binding to UNC45A involves 2 UNC45A monomers per HSP90AB1 dimer. Interacts with CHORDC1. Interacts with DNAJC7 (By similarity). Interacts with FKBP4.

Function:

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Subcellular Location:

Cytoplasm Melanosome

Protein Attributes:

Sequence length:

724

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

724:

SAAVPDEIPP | LEGDEDASRM | EEVD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF02518

KEGG:

mmu:15516

UniGene:

Mm.2180

SMR:

P11499

String:

P11499

Uniprot:

P11499

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ELISA Kit for Mouse Heat shock protein HSP 90-beta

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E10309c

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ELISA Kit for Mouse Heat shock protein HSP 90-beta

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E10309b

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96T

ELISA Kit for Mouse Heat shock protein HSP 90-beta

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E10309r

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96T

ELISA Kit for Mouse Heat shock protein HSP 90-beta

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E10309m

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96T

ELISA Kit for Mouse Heat shock protein HSP 90-beta

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ELISA Kit for Mouse Heat shock protein HSP 90-beta

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E10309h

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96T

CLIA Kit for Mouse Heat shock protein HSP 90-beta

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U10309c

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96T

CLIA Kit for Mouse Heat shock protein HSP 90-beta

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CLIA Kit for Mouse Heat shock protein HSP 90-beta

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U10309r

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96T

CLIA Kit for Mouse Heat shock protein HSP 90-beta

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U10309h

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96T

CLIA Kit for Mouse Heat shock protein HSP 90-beta

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U10309m

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96T

CLIA Kit for Mouse Heat shock protein HSP 90-beta

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U10309b

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96T

Polyclonal Antibody for Mouse Heat shock protein HSP 90-beta

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P10309Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Heat shock protein HSP 90-beta

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P10309Rb-h

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Polyclonal Antibody for Mouse Heat shock protein HSP 90-beta

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P10309Rb-r

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Polyclonal Antibody for Mouse Heat shock protein HSP 90-beta

Monoclonal Antibody for Mouse Heat shock protein HSP 90-beta

Protein for Mouse Heat shock protein HSP 90-beta

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens."
Hoffmann T. , Hovemann B.
Gene74:491-501(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Cloning and nucleotide sequence of the murine hsp84 cDNA and chromosome assignment of related sequences."
Moore S.K. , Kozak C. , Robinson E.A. , Ullrich S.J. , Appella E.
Gene56:29-40(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 2-31; 94-156; 158-161; 467-513; 554-566; 622-640; 684-688 AND 690-720
3.

"Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins."
Moore S.K. , Kozak C. , Robinson E.A. , Ullrich S.J. , Appella E.
J. Biol. Chem.264:5343-5351(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Characterization of the mouse 84-kD heat shock protein gene family."
Moore S.K. , Rijli F. , Appella E.
DNA Cell Biol.9:387-400(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
5.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Kidney.
6.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
7.

"A mouse tumor-specific transplantation antigen is a heat shock-related protein."
Ullrich S.J. , Robinson E.A. , Law L.W. , Willingham M. , Appella E.
Proc. Natl. Acad. Sci. U.S.A.83:3121-3125(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-31 AND 114-125
8.

"The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo."
Minami Y. , Kimura Y. , Kawasaki H. , Suzuki K. , Yahara I.
Mol. Cell. Biol.14:1459-1464(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-6;HOMODIMERIZATION
9.

Lubec G. , Kang S.U. , Klug S. , Yang J.W. , Zigmond M. , Sunyer B. , Chen W.-Q.
Submitted (2009-01) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 42-53; 56-64; 73-95; 149-168; 181-196; 205-219; 250-266; 276-330; 339-347; 360-392; 429-435; 439-448; 457-475; 482-491; 539-552; 558-565; 575-583 AND 624-639
strain: C57BL/6.
strain: OF1.
tissue: Brain.
tissue: Hippocampus.
10.

"Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis."
Chu C.C. , Paul W.E.
Mol. Immunol.35:487-502(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 272-400
strain: BALB/c.
tissue: Spleen.
11.

"Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84)."
Shaknovich R. , Shue G. , Kohtz D.S.
Mol. Cell. Biol.12:5059-5068(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 531-724
tissue: Heart.
12.

"Phosphoproteomic analysis of the developing mouse brain."
Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-255;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic brain.
13.

"Mammalian CHORD-containing protein 1 is a novel heat shock protein 90-interacting protein."
Wu J. , Luo S. , Jiang H. , Li H.
FEBS Lett.579:421-426(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CHORDC1
14.

"Proteomic identification of proteins conjugated to ISG15 in mouse and human cells."
Giannakopoulos N.V. , Luo J.K. , Papov V. , Zou W. , Lenschow D.J. , Jacobs B.S. , Borden E.C. , Li J. , Virgin H.W. , Zhang D.E.
Biochem. Biophys. Res. Commun.336:496-506(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ISGYLATION
15.

"Quantitative time-resolved phosphoproteomic analysis of mast cell signaling."
Cao L. , Yu K. , Banh C. , Nguyen V. , Ritz A. , Raphael B.J. , Kawakami Y. , Kawakami T. , Salomon A.R.
J. Immunol.179:5864-5876(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-484;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Mast cell.
16.

"A differential phosphoproteomic analysis of retinoic acid-treated P19 cells."
Smith J.C. , Duchesne M.A. , Tozzi P. , Ethier M. , Figeys D.
J. Proteome Res.6:3174-3186(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-255 AND SER-261;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Teratocarcinoma.
17.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-226; SER-255 AND SER-261;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
18.

"Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-305;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
19.

"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H. , Ye M. , Dong J. , Han G. , Jiang X. , Wu R. , Zou H.
J. Proteome Res.7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-255;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
20.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-255;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.

"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-255;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
22.

"Mapping of O-GlcNAc sites of 20 S proteasome subunits and Hsp90 by a novel biotin-cystamine tag."
Overath T. , Kuckelkorn U. , Henklein P. , Strehl B. , Bonar D. , Kloss A. , Siele D. , Kloetzel P.M. , Janek K.
Mol. Cell. Proteomics11:467-477(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT SER-434 AND SER-452
tissue: Liver.
23.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-624;SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-219; LYS-531 AND LYS-577;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.

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